BP-2000 Blood Pressure Analysis System™ for Mice and
Rats
Thank you for your interest in the BP-2000 Blood Pressure Analysis
System™. The BP-2000 is the computerized, non-invasive tail-cuff system
that has revolutionized the process of measuring mouse and rat blood
pressure. In use in more than 100 research laboratories worldwide, it
is the de facto standard in transgenic and knockout mouse
research. The BP-2000 has been shown in peer-reviewed scientific research to give results that correlate closely with interarterial measurements (Krege JH, Hodgin JB, Hagaman JR, Smithies O, Hypertension. 1995; 25: 1111-1115).
The BP-2000 can rapidly
make multiple measurements simultaneously on up to four animals, without
operator intervention. With the BP-2000, you can efficiently and
accurately measure blood pressure on large animal populations, for
high-throughput phenotyping. The BP-2000 is capable of making measuring on one, two, or four
animals simultaneously, depending on the model. The BP-2000 can
be expanded as your research needs grow. For example, if you purchase a
single-channel system, you can later expand it to a two- or four-channel
system by simply upgrading your specimen platform. Similarly, you can start
out with a mouse system, and later add rat capability, by getting an
additional specimen platform - at a fraction of the cost of a new system. The BP-2000 offers unprecedented ease in managing your blood
pressure data. The built-in database instantly stores the results of
every measurement. The powerful Report Wizard™ allows you to
quickly create customized data reports that contain just the data you want to
see, in the way you want to see it. The data can be exported directly to
Microsoft Excel®, or imported into statistics programs for further analysis. A large and ever-growing number of research
papers have been published based on data obtained with the BP-2000
Blood Pressure Analysis System™. With the BP-2000, you can
rest assured that you are working with proven and accepted technology. BP-2000 Features
·
The de facto standard for
non-invasive blood pressure analyzers in transgenic and knockout mouse
research. ·
Used worldwide in more than 100 laboratories. ·
Cited in more than 80 peer-reviewed research
publications. ·
Specifically validated in peer-reviewed
scientific research (Krege JH, Hodgin JB, Hagaman JR, Smithies O, Hypertension.
1995; 25: 1111-1115). ·
Shown to give results that correlate closely
with interarterial measurements. ·
Measures systolic, diastolic, and mean blood
pressure, and heart rate. ·
Capable of making measuring on one, two, or
four animals simultaneously, depending on model. ·
Easily upgrade to additional channels
(maximum of four), or add ability to measure both rats and mice, by
purchasing a new Specimen Platform - at a fraction of the cost of a whole
system. ·
Intuitive, powerful analysis software
displays, measures, and stores blood pressure, heart rate, and waveforms. ·
Powerful Report Wizard™ lets you create
reports with just the data you want, in the way you want to see it. ·
Automatic temperature control. ·
Precision-engineered cuff
elastic gives excellent channel-to-channel consistency. ·
Exports data directly to Excel®.
·
Includes a notebook computer and BP-2000
analysis software.
We hope that you will find the BP-2000 Blood Pressure Analysis
System to be a valuable and effective tool in your research. If you have
any further questions, please do not hesitate to contact us.
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BP-2000 Product Catalog
Complete Mouse Systems
Item
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Description
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BP-2000-M-1 |
BP-2000 Blood Pressure Analysis System, with Single-Channel
Mouse Platform, Control Unit, Notebook Computer, Analysis Software License,
Accessories Kit, and one Mouse Holder (specify size) |
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BP-2000-M-2 |
BP-2000 Blood Pressure Analysis System, with Two-Channel
Mouse Platform, Control Unit, Notebook Computer, Analysis Software License,
Accessories Kit, and one set of Mouse Holders (specify size) |
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BP-2000-M-4 |
BP-2000 Blood Pressure Analysis System, with Four-Channel
Mouse Platform, Control Unit, Notebook Computer, Analysis Software License,
Accessories Kit, and one set of Mouse Holders (specify size) |
Complete Rat Systems
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BP-2000-R-1 |
BP-2000 Blood Pressure Analysis System, with Single-Channel
Rat Platform, Control Unit, Notebook Computer, Analysis Software License,
Accessories Kit, and one Rat Holder (specify size) |
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BP-2000-R-2 |
BP-2000 Blood Pressure Analysis System, with Two-Channel
Rat Platform, Control Unit, Notebook Computer, Analysis Software License,
Accessories Kit, and one set of Rat Holders (specify size) |
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BP-2000-R-4 |
BP-2000 Blood Pressure Analysis System, with Four-Channel
Rat Platform, Control Unit, Notebook Computer, Analysis Software License,
Accessories Kit, and one set of Rat Holders (specify size) |
Combined Mouse and Rat Systems
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BP-2000-MR-1 |
BP-2000 Blood Pressure Analysis System, with |
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BP-2000-MR-2 |
BP-2000 Blood Pressure Analysis System, with |
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BP-2000-MR-4 |
BP-2000 Blood Pressure Analysis System, with |
Mouse and Rat Holders
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BP-MH0 |
Mouse Holder, Size 0 - for very small mice |
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BP-MH1 |
Mouse Holder, Size 1 - for animals under 30 grams |
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BP-MH2 |
Mouse Holder, Size 2 - for animals 30-45 grams |
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BP-MH3 |
Mouse Holder, Size 3 - for animals larger than 45 gm |
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BP-RH1 |
Rat Holder, Size 1 - for animals under 250
grams |
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BP-RH2 |
Rat Holder, Size 2 - for animals 250-400 grams |
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BP-RH3 |
Rat Holder, Size 3 - for animals 400-550 grams |
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NI BP Recorder family by Panlab Working
range: 0 - 300 mm Hg. - A
silent built-in air pump ensures automated cuff inflation/deflation at a very
constant rate. -
Easy to use: press only one button to start the measurement process - A
digital display shows the Systolic, Diastolic and Mean blood pressure &
the Heart rate. The digital display also shows the level of the pulse signal. - All units can be used indistinctly for rats, mice, dogs, using specific pulse transduc. & cuff -
Analog outputs allow for the recording of the cuff pressure and pulse
signals. -
Total reliability to realise consecutive measurements on the same animal -
Possibility of monitoring the pressure curve and the heart rate in a PC Option 05PL All
the models can be supplied with the Option 05PL to monitorize and analyse
directly pressure and heart rate in the PC. |
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Model |
Data Memory |
RS
232 |
Connection
to Heater/Scanner |
Programmable |
Statistics |
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LE 5001 |
No |
No |
Yes(Manual
Switch) |
No |
No |
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LE 5002 |
Up to
6.000 |
Yes |
Yes(Manual
Switch) |
No |
No |
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LE 5007 |
Up to
6.000 |
Yes |
Yes(Automatic
Switch) |
Yes |
Yes |
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Heater for Single Holder LE 5610 Provides
a comfortable and heated environment, necessary to produce peripheral
vasodilation and isolate the animal from external noise Heater / Scanner In addition to provide an adequate environment
for NIBP measurement, allows to measure it with all the NIBP Systems in
several animals: • Manually switching (up to 6 animals) in
models LE 5640/6 (Rats) and LE 5655/6 (Mice) |
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Very useful to pre-warm animals before carrying out Non
Invasive Blood Pressure measurements on their tail. This save times, ensures more reliable results and enables the
operator to measure quickly large numbers of
animals. The lamp can also be used to warm animals after surgery
and it can be driven by a rectal probe and thermostatic electronic unit .
Power is 250 W. Code
LIR 250W Infrared Lamp Code HB
121
Electronic unit with rectal probe (specify mouse or rat) |
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INVASIVE MEASUREMENTS
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Blood Pressure Transducer SP 844
SP 844 can be used for the direct arterial and
venous pressure measurement in animal blood vessels. Range –30 +300 mmHg. Sensitivity
50uV/V/cmHg Code SP 844 Blood Pressure Transducers Code SP DOM Pkg of 50 sterile interchangeable domes Code STK Pkg of 10 3 way stopcock |
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LOW COST Blood Pressure
Transducer BLPR2
BLPR can be used for the direct arterial and
venous pressure measurement in animal blood vessels. Range –30 +300 mmHg. Sensitivity
50uV/V/cmHg Code BLPR2 Blood Pressure Transducers Code STK Pkg of 10 3 way stopcock |
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BLOOD PRESSURE MONITOR Analog single-channel transducer signal
conditioner An analog signal conditioner for monitoring pressure, force, temperature, and other physical parameters provided by transducers, BP-1 Pressure Monitor is designed to monitor animal arterial or venous blood pressure, displaying systolic, diastolic or average blood pressure. BP-1 accepts any blood pressure transducer as well as other transducers (force, temperature, etc). An audio monitor provides a signal with variable pitch and amplitude, allowing you to hear changes in blood pressure. Digital LCD display provides average or peak signal values from 0 to 1999 mV. |
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When supplied with an optional pressure gauge, the LCD shows pressure in mm Hg. Recorder output connector allows direct connection to a pen recorder, oscilloscope or computer front end. Code BP-1 Blood Pressure Monitor |
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Make your
own catheters by our PE & Silastic Tubing coils, click here: PE & Silastic Tubing
Special
catheters Home Made Luer-Lock Fitting available on request
A wide range
of any Kind of Catheters available here: WIDE RANGE OF CATHETERS
DATA ACQUISITION SYSTEM FOR BLPR RECORD. & ANALYSES, click here:
MP
Biopac DAC
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LATEX BALLOONS
The balloon catheter 170423 (for sizes 3-4)and 170424 (for sizes 5-6)
are for ventricular insertion. It is a simple, reliable way to measure left
ventricular isovolumetric pressure.
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Pressure Calibrators
Friendly,
easy to use Mercury or analog PRESSURE CALIBRATOR. Very
useful to calibrate and check Range in Blood Pressure Transducers and in the
Non Invasive BP Recorder apparatus.
Range 0-200 mmHg. Code
HGCAL
Mercury Pressure manometer
(picture at right) Available in 3
colors: Blue, Red, Green Code
ANHGCAL
Analog Pressure Calibrator
(picture at left) |
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Cardiac Output Computer: Cardiomax III
The Cardiomax-III Thermodilution Cardiac Output Computer doubles as a physiological data acquisition system. The new thermodilution
cardiac computer interfaces directly to a Pentium desktop or laptop computer
via a very fast RS-232 link. It is intended to be used on a variety of lab
animals from mice to horses. In addition to measuring cardiac output and
associated parameters (SV, HR), the Cardiomax-III can be used to measure,
display, and log ECG (EKG) with its own low level amplifier and two (2) blood
pressures (DP, MP, SP, dp/dt). Storage of all parameter data is provided in
comma separted ASCII format for easy import into a variety of analysis
programs. The thermo-dilution curve image can also be saved. The
Cardiomax-III can use a variety of thermistor catheters as well as Columbus
Instruments' thermocouple microprobes. The Cardiomax-III's special design
makes it resistant to external radio signal interference and its small size
(35.5 x 29 x 10 cm) makes it very convenient in a crowded laboratory
environment. |
Code Cardiomax III Including transducers, temperature probes and
software to PC |
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MPMS 100 Micro Pressure Measurement System The Micro Pressure Measurement System is the complete solution for
demanding pressure measurements using advanced optoelectronic technology—and
is the premier choice for a variety of pressure measurements where accurate
data, high speed, or small size are key features. The sensors are very small and well suited for application areas such
as: cardiovascular blood pressure, LVP from within the heart of a small
animal (mouse), intracranial pressure, intervertebral disc pressure,
pediatric intensive care respiratory monitoring, muscle pressure, and
pressure in the bladder or in the urinary tract. |
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Intelligent electronics in conjunction with fiber optics produce accurate
data at high speed, making instantaneous pressure change analysis possible.
The electromagnetic immunity inherent in the technology makes pressure
measurement trouble-free, even in environments with high electromagnetic
field strength—such as in MRI applications. The system consists of an MPMS100 Control Unit and a TSD170 series
Micro Pressure Transducer (separate purchase). TSD170 Micro Pressure Transducer TSD171 Micro Pressure Transducer,
radio opaque (MRI-compatible) The Ø 0.42 mm optical transducer
is very stable, has a low temperature coefficient, and is easy to use. The
transducer is biocompatible and has intrinsic electrical isolation. The micro
dimensions of the transducer tip ensure a well-defined measurement location
and minimal influence on the measurement environment. The Control Unit is based on advanced optoelectronic technology. All
settings can be made on the front panel. Analog output and serial RS232 make
connection with a BIOPAC MP Unit easy. Measurement data can be monitored in
real time and stored for further data analysis. |
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Veterinary Patient MONITOR -
Code 33721
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CARDIO-3M - 3 cannel ECG with monitor - LCD display, 1 or 3
channels in Standard or Cabrera format with base line setting. - High
resolution thermal printer (8 dots/mm): hardcopy 1 or 3 channels real time
with possibility to print the millimetric grid. - Recording manual or automatic
- Memory 10 seconds for each lead - Image freeze with memory scrolling for reviewing
and hard copy of acquired signals - Digital filters for elimination of muscle
tremors, power line and base line disturbs |
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PORTABLE ECOGRAPH - 10” SVGA monitor with one
probe connector, without probes. Code 33332 Portable Ecograph A wide range of probes available |
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Automated Blood Sampler Instech's ABS110 automates
the collection of blood samples from a range of laboratory animal species
including rats, dogs and non-human primates. By eliminating labor-intensive
periodic manual withdrawals it can streamline drug metabolism and pharmacokinetics
studies. It also reduces the stress on animals that frequent handling can
cause. The automated sampler withdraws blood from a freely-moving animal
according to your programmed schedule, stores the samples in an integrated
refrigerated fraction collector, and replaces the withdrawn volumes with IV
fluid. It does all this work using only one fluid channel, leaving you a free
channel on a dual channel swivel for drug infusion, blood pressure monitoring
or other applications. An automatic calibration routine gives you the
flexibility to choose the catheters and tubing sets that work best for you. And
you can control and monitor sampling schedules, volumes and withdrawal rates
for up to twelve animals from a single PC or laptop. The system uses a series
of four integrated precision peristaltic pumps to sample blood, replace
fluids, inject air bubbles (to separate samples) and dispose of waste fluid. A
fifth pump is provided for IV drug administration or other applications using
a separate fluid channel |
Restrainers and Tailveiner
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The
TAILVEINER® is the first easy to use mouse and rat restrainer specifically
designed for tail vein injections. The slotted tube permits the rat or mouse to
be quickly pulled in by the tail. The animal is then restrained by a tapered
plug which slides easily to accommodate any size rat or mouse, but locks
automatically when handle is released. The tailveiner® is the fastest
restrainer yet for intravenous injections in small animals. Code
TV 150
Tailveiner for Mice Code
RTV 170 Tailveiner for Rats up to 120 grams Code
RTV 180 Tailveiner for Rats up to 350 grams Code
RTV 190 Tailveiner for Rats up to 500 grams Restrainers: The most
common used Rodent Restrainers especially suitable for BP measurement.
Conditioning of the animal is advisable before starting real treatment. Code
LE 5016 Restrainers for Mice up to 35 grams Code
LE 5018 Restrainers for Mice up to 50 grams Code
LE 5020 Restrainers for Rats up to 150 grams Code
LE 5024 Restrainers for Rats up to 400 grams Code
LE 5025 Restrainers for Rats up to 500 grams Restrainer for bigger animals (Rabbits) available |
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Circular
cages hold up to 10 mice or 11 rats. The notched removable lid can be dialed
to any of the ventilated pie- shaped chambers. These units were originally
designed for whole body irradiation. Use for temporary transport or storage
of animals for acute studies. The rat cage has tail slots for intravenous
dosing. Code
MPC Mouse Pie Cage Code
RPC-1 Small Rat Pie Cage (up to 250 grams) Code
RPC-2 larger Rat Pie Cage (up to 400 grams) |
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2Biological
Instruments
via L. Da Vinci 2C - 21023 Besozzo
VA Italy
tel. +39 0332 773210 Fax +39 0332 970141