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NEW Vibrating Microtome |
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MODEL HA752
with manual tissue transport MODEL MA752
with motorized tissue transport MODEL ROMA752
with motorized tissue transport &
remote operation. 7550/1SS Pkg 50 Stainless S.
Blades 7550/1C Pkg 5 Ceramic Blades 752/1SS Pkg 50 Stainless S. Blades (for old units
only, before 2000) |
The instrument
has been designed to cut 50 to 700 micron sections of fresh, unfixed tissue
for in vitro recordings, tissue culture and microassay work. It can also be used
to section fixed tissue down to 20 microns without previous embedding or
freezing. The Vibroslice has also been redesigned and considerably upgraded
in its performance from the original specification and will section tissue
such as brain stem, and liver maintaining the integrity of surface cells for
recording. A vibrating blade slices tissues without the traumatic damage of
other methods. The blade oscillates at a fixed lateral displacement of 1.0mm
at a frequency set by the user and then actuated by a footswitch. If damage
should occur to the blade this lateral displacement minimizes scoring of the
tissue. Both frequency
of the blade oscillation and the rate of advance of the section are important
in producing good quality sections. The Vibroslice is designed to be flexible
in its operation and has a removable tissue holder and bath, which allows
tissue to be prepared and stored ready for later use, provides easy cleaning
and prevents carryover of fixative between fixed and unfixed tissue. Recent
product redesign has incorporated a variable angle blade holder for the first
time. The advance
speed on the motorized models is now ultra-low being half of the previous
model and the speed of oscillation has been raised again. Changing of drive
belts is now much easier with the readily removable molded cover. |
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Integraslice is designed to produce the very highest quality of slices in the most difficult tissue slicing application. Robust in design and built from the highest specification components, both models accommodate the following optional equipment: - · Campden Instruments precision blade technology in stainless steel or zirconium ceramic. · Tissue baths and cutting heads that can be removed for autoclaving or simply cleaning. · Optional, integrally fitted Inspection Microscope and / or Cold Light Source. · Optional Tissue Bath with Temperature Controller to cool or warm to +/- 0.5o C. MODEL
7550PSDS for fully Programmable cutting profiles of Speed, Distance and Section thickness. Features include Dynamically Adjustable Speed and Amplitude [DASA] MODEL
7550MM for Motorised or Manual advance of the oscillating blade 7550/1SS Pkg 50 Stainless S. Blades 7550/1C Pkg 5 Ceramic Blades |
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The McIlwain Tissue Chopper has been designed to prepare samples of tissue for metabolic experiments and is particularly suitable for small and irregular samples for biopsy or from small organs. For Neuroscience it offers the opportunity for rapid chopping of tissue such as hippocampus, which is relatively, flat and will not suffer excessive stress damage. For slicing cortical or sub-cortical regions Campden’s "Vibroslice" will provide precise and gentle slice sectioning. The tissue chopper is also good for preparing cell cultures from the brain of young animals. Its operation
is such that it will cause much less disturbance of cell structure than would
a blender or homogeniser, and it can be used on fragments which would be
difficult to cut by ordinary methods. Typical applications are for liver,
kidney and parts of the central nervous system. Preparation of 1mm thick
slices or cubes and prism samples can be prepared in 30 seconds. The Chopper
offers stepless variation of slice thickness from zero to maximum by means of
an indexing clutch in conjunction with micrometer head calibrated in microns. Code
TC752 |
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The 7600 enables the cooling of physiological fluid and tissue from normal room temperature to freezing point in approximately 5 to 6 minutes. The 7600 Cooler will achieve zero in about 4 minutes and has the capacity to go as low as minus 2 celcius. The result of slicing at correct temperature is twofold. Firstly the slice quality is improved and secondly the unfixed tissue is preserved for in vitro recording. Fresh tissue needs to be cooled as rapidly as possible to reduce its oxygen demand whilst perfusing, typically with 5% oxygen. The cooled bath fits onto the Vibroslice exactly as the standard bath and takes its power from the nearby control unit. Cooler for Vibroslice/Integraslice model 7600 |
Tissue Slicer Originally designed to prepare thin slices of living brain, the tissue slicer is also excellent for slicing other tissues, in the blocking of fixed tissue for histology, and in the slicing of electrophoretic gels. Sections as thin as 150 microns can be reliably prepared. The 51425 Tissue Slicer has a conventional vernier micrometer, with a resolution of 10 microns. The 51415 Digital Tissue Slicer has a digital display electronic micrometer, with 1 micron resolution. Switch from mm to inches, set zero at any point, set low and high tolerance limits. Features an over-travel warning signal and output to a printer, processor, data logger or computer. Code 51425 Manual Tissue Slicer Code 51415 Digital Tissue Slicer |
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RODENT BRAIN MATRIX-RBM
We offer one
of the largest selections of brain matrices available. Made of acrylic, or stainless
steel, these matrices are sturdy and can be heated, chilled, autoclaved
(stainless steel only), scrubbed and stand up to rigorous daily use. Coronal
matrices have the additional feature of a mid-line sagittal cut to facilitate
splitting of the left and right hemispheres. Sections can be as fine as 1 mm.
The olfactory/spinal/notch is cut into each matrix. Code: BLADES
: Pkg of 100 blades for Brain Matrix RBMA-200C Adult Mouse Coronal - Plastic RBMA-200S Adutl Mouse Sagittal - Plastic RBMA-300C Rat 175-300 g Coronal - Plastic RBMA-300S Rat 175-300 g Sagittal - Plastic |
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RBMA-600C Rat 300-600 g Coronal - Plastic RBMA-600S Rat 300-600 g Sagittal - Plastic RBMS-200C Adult Mouse Coronal – Stainless
Steel RBMS-200S Adutl Mouse Sagittal - Stainless Steel |
RBMS-300C Rat 175-300 g Coronal - Stainless Steel RBMS-300S Rat 175-300 g Sagittal - Stainless Steel RBMS-600C Rat 300-600 g Coronal - Stainless Steel RBMS-600S Rat 300-600 g Sagittal - Stainless Steel |
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Slice Workstation' Multichannel Observation SystemsCode 746 is
a Slice Workstation intended for the
simultaneous evaluation or observation of either 4 or 8 slices in submerged or
interface type chambers. Details of the slice chambers are available on
request. |
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Slice Chambers for Blind Patching &
Extracellular Recording
Model 745
Series (E)
Compact and modular; easy to set up, easy to swap between submerged and interface modes. Consistently stable fluid flow and stable temperature. The Chambers Manufactured from Plexiglas, or, for pharmacological or toxicological studies chemically inert p.t.f.e. (Teflon®) to avoid adhesion of drugs. Ag/AgCl reference electrodes included with termination points, easily replaceable The one, two or four channel chambers can be used either in the classical submerged [Oslo type] or in the air/fluid interface [Haas Type] with humidified atmosphere above the tissue slices. To convert from submerged to interface type, simply exchange the chamber top plate Heated water
bath has a low noise heating element and gas tube to prevent oxygen loss from
perfusate solution. Holding chamber
for incubation of slices until transfer to recording chamber. Stable Temperature control by dual
thermistor feedback from water bath and slice chamber. Ergonomic design for
access from either side with micromanipulators |
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Brain - Action Potentials from Hippocampal Slice Heart - Double Pulse Stimulation
to evaluate refractory period of cardiac action potential recorded from
ventricular part of the cardiac tissue slice. |
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Visual Patching and Imaging
Chamber Model 7800 Series
The Chamber Just put it on
the microscope stage, plug in the controller, connect the tubing and switch
it on. Objective lens heater plugs into controller to provide unobtrusive
control of the environment above the chamber. Low profile for easy access of
electrodes under the heated objective lens when mounted on upright
microscopes. No electromagnetic noise emission from the DC power source.
Annular ring adapter to fit all types of upright and inverted microscopes.
Adapts to 22mm coverslip or 35mm petri dish. Laminar flow of fluids across
the centre of the chamber. Chambers are coated with chemically inert
p.t.f.e. (Teflon®) to avoid adhesion of drugs. Gas inlet through heat
exchanger into chamber for hypoxia studies, hydrophobic p.t.f.e. resists
flooding into gas inlets. Unique design of suction capillary ensures a steady
state of flow and a mill pond smooth surface in a shallow pool of 1mm depth.
Ag/AgCl reference wire is simply placed within the chamber. Vented lid seals
the chamber for hypoxia studies. |
Applications: - Electrophysiology - Imaging - Including studies with hypoxia |
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Electronic digital calipers are a joy to work with. Readings in inches or metric at the touch of a button. Resolution of .001” or 0.01 mm. Floating zero feature allows scale to read plus or minus a set point without calculations. Stainless steel. Lockable. Code 58750 Digital Caliper |
Non-rotating Spindle Digital Micrometer HeadBuild your own precision micro-positioning device. The new non-rotating
spindle digital micrometer head allows you to create your own
micro-positioning instrument. With micron-level accuracy, it gives higher
precision than a normal micromanipulator. Since the spindle does not rotate
as it advances, instruments can be directly attached without the need for a
complicated decoupling device. The digital display eliminates the need to
squint at the notational scale. Readings can be clearly seen in either inches
or millimeters. You can read both absolute position and the increment
relative to a previously chosen point. In addition, there is a digital output
port. With optional cable and software SPG-KIT-MICRONR, you can send
measurements to your computer either continuously or every time a button on
the micrometer is pushed. Code 502102 |
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2Biological Instruments
via L. Da Vinci 2C -
21023 Besozzo VA Italy
tel. +39 0332 773210 Fax +39 0332
970141